The central theme of our interdisciplinary research is the emerging area of adaptable supramolecular functional materials. We attempt to innovate on new materials and chemistries to achieve practical applications. Understanding the structure-activity relationship of those materials allows us to design useful biocompatible materials.  We actively explore the role of biomaterial surface chemistry in modulating the material-biology interface. Such work is crucial for biological applications of materials, given the central role of surface chemistry in constructing biomaterials with appropriate functionalities and biocompatibility. Our research has demonstrated the utility of these novel materials in different bio-applications, including diagnostics, biocatalysis, therapeutic delivery, enzyme mimicking, protocell fabrication, and environmental remediation. Long-term, we aim to innovate effective point-of-care diagnostics for different diseases with personalized screening abilities, novel platforms for precision medicine, and tissue engineering incorporating the desired material properties.